Anatomically
Proven
Soothe the Skin โ Lycopus Lucidus Leaf Extract
After extensive anatomical research on the skin, among countless botanical ingredients,
it was Lycopus lucidus leaf extract that proved to stabilize the skin barrier and cellular responses from the ground up.
Animals in an atopic dermatitis model treated with Lycopus Lucidus Leaf Extract showed remarkable recovery of skin tissue.
็ป่ฟๆณฝๅ ฐๅถๆๅ็ฉๅค็็็นๅบๆง็ฎ็ๆจกๅๅจ็ฉ๏ผๅ ถ็ฎ่ค็ป็ปๆพ็คบๅบๆพ่็ไฟฎๅคๆๆใ
Scientifically Proven to Restore Deep Skin Layers
As demonstrated in the study above, Lycopus Lucidus Leaf Extract penetrates beyond the skin surface and delivers restorative effects deep within the dermal layers.
The top-left photo shows healthy skin, while the top-right image depicts inflammation and swelling after induced irritation. The lower images show visible recovery when treated with Lycopus Lucidus Leaf Extract.
Application of Lycopus Lucidus Leaf Extract visibly repaired damaged tissue and reduced inflammation, confirming its proven efficacy in soothing sensitive skin.
็ป็งๅญฆ้ช่ฏๅฏไฟฎๅคๆทฑๅฑ่่ค
ๅฆไธๅพๆ็คบ๏ผๆณฝๅ ฐๅถๆๅ็ฉไธไป ไฝ็จไบ็ฎ่ค่กจ้ข๏ผ่ฟ่ฝๆทฑๅ ฅ็็ฎๅฑๅๆฅไฟฎๅคๅๆใ
ๅทฆไธๅพไธบๅฅๅบท็ฎ่ค๏ผๅณไธๅพๆพ็คบ่ฏฑๅฏผๅบๆฟๅๅบ็ฐ็็็ไธ่ฟ่ใไธๆนไธคๅผ ๅพไธบไฝฟ็จๆณฝๅ ฐๅถๆๅ็ฉๅ๏ผ็ฎ่คๆพ่ๆขๅค็ๆๆใ
ๆณฝๅ ฐๅถๆๅ็ฉ็ๅบ็จๆๆไฟฎๅคๅๆ็ป็ปๅนถๅ่ฝป็็๏ผ่ฏๅฎๅ ถๅจ่็ผๆๆ่ๆน้ข็็งๅญฆๅๆใ
Phenolic and Flavonoid Complex for Skin Soothing and Recovery
Extensive research has demonstrated that Lycopus Lucidus Leaf Extract directly interacts with cellular signaling pathways involved in skin sensitivity and inflammation.
Specifically, the activation marker of NF-ฮบB, a key regulator of inflammatory responses, improved by approximately 50%, while the activation marker of MAPK, another stress-response pathway, was reduced by 40%.
These findings provide strong evidence that Lycopus Lucidus Leaf Extract acts at the very first stage of the skinโs sensitivity responseโthe โalarm switchโโeffectively calming excessive reactivity and restoring balance.
Phenolic & Flavonoid ๅคๅ็ฉๅฉๅ่็ผไธไฟฎๅค่่ค
ๅคง้็ ็ฉถ่กจๆ๏ผๆณฝๅ ฐๅถๆๅ็ฉๅฏ็ดๆฅไฝ็จไบไธ็ฎ่คๆๆๅ็็็ธๅ ณ็็ป่ไฟกๅท้่ทฏใ
ๅ ทไฝ่่จ๏ผ็็ๅๅบๅ ณ้ฎ่ฐๆงๅ ๅญ NF-ฮบB ็ๆฟๆดปๆๆ ๆนๅ็บฆ 50%๏ผ่ๅบๆฟๅๅบ้่ทฏ MAPK ็ๆดปๅๆฐดๅนณ้ไฝไบ 40%ใ
่ฟไบ็ปๆๅ ๅ่ฏๆ๏ผๆณฝๅ ฐๅถๆๅ็ฉๅฏๅจ็ฎ่คๆๆๅๅบ็ๆๅ้ถๆฎต๏ผๅณโๆฅ่ญฆๅผๅ ณโ๏ผๅๆฅไฝ็จ๏ผๆๅถ่ฟๅบฆๅๅบๅนถๆขๅค่่คๅนณ่กกใ
Kim et al. (2021), Journal of Inflammation Research
Kim ็ญ (2021)๏ผ็็็ ็ฉถๆๅฟ
Min et al. (2021), Molecular Medicine Reports
Min ็ญ (2021)๏ผๅๅญๅปๅญฆๆฅๅ
Cross-Verification through Global Research
Study 1: Min et al. (2021), Molecular Medicine Reports
This study used an animal model designed to simulate highly sensitive skin conditions.
It was confirmed that the activation of NF-ฮบB and MAPK signaling within the skin tissue was significantly reduced.
้่ฟๅ จ็็ ็ฉถไบคๅ้ช่ฏ
็ ็ฉถ 1๏ผMin ็ญ (2021)๏ผๅๅญๅปๅญฆๆฅๅ
ๆฌ็ ็ฉถ้็จๅจ็ฉๆจกๅๆฅๆจกๆ้ซๅบฆๆๆ็็ฎ่ค็ถๆใ
็ปๆๆพ็คบ๏ผ็ฎ่ค็ป็ปๅ
็ NF-ฮบB ไธ MAPK ไฟกๅท้่ทฏๆฟๆดปๆพ่้ไฝใ
Study 2: Shin et al. (2005), Archives of Pharmacal Research
This study revealed that Lycopus Lucidus Leaf Extract reduces the secretion of inflammatory substances from cells responsible for triggering immediate skin sensitivity reactions.
This means that Lycopus Lucidus Leaf Extract not only soothes already activated skin responses but also helps prevent the initial cascade of sensitivityโacting proactively to calm the skin before irritation begins.
็ ็ฉถ 2๏ผShin ็ญ (2005)๏ผ่ฏ็ฉ็ ็ฉถๆกฃๆก
็ ็ฉถ็ปๆ่กจๆ๏ผๆณฝๅ ฐๅถๆๅ็ฉๅฏๆๅถ่ด่ดฃๅผๅ็ฎ่คๅณๅปๆๆๅๅบ็็ป่ๅๆณ็็็ฉ่ดจใ
่ฟๆๅณ็ๆณฝๅ ฐๅถๆๅ็ฉไธไป ่ฝ่็ผๅทฒ่ขซๆฟๆดป็็ฎ่คๅๅบ๏ผ่ฟ่ฝๅจๆๆๅๅบ้พๅฏๅจๅๅๆฅ้ข้ฒไฝ็จ๏ผไธปๅจๅฎๆ่่ค๏ผ้ฒๆญขๅบๆฟๅ็ใ
Shin et al. (2005), Archives of Pharmacal Research
Shin ็ญ (2005)๏ผ่ฏ็ฉ็ ็ฉถๆกฃๆก
Proprietary Patent of Lesstopy Unveiling the Mechanism of Skin Recovery
The soothing and moisturizing mechanism of Lycopus Lucidus Leaf Extract goes beyond simple efficacy โ it has been scientifically proven to enhance the skinโs natural ability to recover.
Based on these research findings, Lesstopy has obtained a proprietary patent for the composition of Lycopus Lucidus Leaf Extract.
Lesstopy ็ฌๅฎถไธๅฉ ๆญ็คบ่่คไฟฎๅคๆบๅถ
ๆณฝๅ
ฐๅถๆๅ็ฉ็่็ผไธไฟๆนฟๆบๅถไธไป
ไป
ๅ็ๅจๅๆๅฑ้ข๏ผ
็งๅญฆ็ ็ฉถๅทฒ่ฏๅฎๅ
ถ่ฝๅคๅผบๅ่่ค็่ช็ถไฟฎๅคๅใ
ๅบไบ่ฟไบ็ ็ฉถๆๆ๏ผLesstopy ่ทๅพไบๅ ณไบๆณฝๅ ฐๅถๆๅ็ฉ้ ๆน็ปๆ็็ฌๅฎถไธๅฉใ
*Patent No. 10-2144566
